drawback

disadvantage

Synonyms: check, defect, deficiency, detriment, difficulty, disability, evil, failing, fault, flaw, fly in the ointment, handicap, hindrance, hitch, ill, impediment, imperfection, inconvenience, lack, nuisance, obstacle, shortcoming, snag, stumbling block, trouble, weakness

Antonyms: advantage, benefit, boon, extra, perfection

Slow drying is the chief drawback of this paint.